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Tuesday, 8 February 2011

Sensitive and specific Chromatin Immunoprecipitation assay kit

Porvair Filtration Group, a leading innovator in the fields of filtration and separation, has developed a new technology that has particular relevance to the rapidly expanding Epigenetics market and will be unveiling it at the Epigenetics World Congress in Boston in April 2011.

Chromatin Immunoprecipitation (ChIP) is the key experimental technique used to investigate the interaction between proteins and DNA in the cell. It aims to determine whether specific proteins are associated with specific genomic regions. ChIP is a core enabling technique that is being widely adopted in the rapidly growing field of Epigenetics.

Using a new approach, based on a rigid porous polymer matrix rather than the traditional sepharose or magnetic beads, Porvair has developed a novel Chromatin ImmunoPrecipitation (ChIP) assay kit called Chromatrap.

Results from third party field trials, to be presented at the Epigenetics World Congress, demonstrate that Chromatrap is able to routinely deliver greater ChIP specificity, higher ChIP sensitivity and faster separations than traditional sepharose or magnetic bead approaches.

Porvair Filtration Group