Wednesday 29 September 2010

Capsule-based drug delivery at CPhI-ICSE 2010

Capsugel, a provider of dosage form solutions to the pharmaceutical and related healthcare industries, will be present its innovative drug delivery technologies at the CPhI/ICSE show in Paris, France.

Capsugel will highlight its capsule technology for use in Dry Powder Inhalers (DPIs) with experts on hand to discuss how its capsule design has been adapted to optimize puncturing and retraction behaviour, which can be critical in helping deliver the correct dose from a DPI. Capsugel’s experts will explain how Capsugel’s technology can be used to provide flexible and value-added dosage form solutions for challenging therapeutic applications.
The company will also showcase Vcaps Plus capsules, its new generation of hypromellose-based two piece capsules, for optimizing drug delivery. This exciting capsule offers immediate release of active pharmaceutical ingredients (APIs), and provides pH-independent dissolution. It is well suited for hygroscopic compounds, as well as formulations that include materials that are moisture sensitive or chemically unstable. Additionally, Vcaps Plus capsules are suitable for patients that prefer vegetarian capsules for ethical or cultural reasons.

Capsugel will be featuring the Product Development Centres and highlighting Capsugel’s Ploërmel, France facility. At these centres, clients can have lipid-based or powder filled capsule products developed using a range of liquid filling and powder dosing equipment including Capsugel’s unique Xcelodose precision powder microdosing system that can reproducibly fill precise powder doses as low as 100µg. This combination of equipment and expertise means clients can use Capsugel facilities for every phase of clinical development right through to commercial manufacture of their liquid capsule products.

“We are delighted to be focusing this year at CPhI/ ISCE on our range of ready-to-use solutions for producing both powder and liquid filled capsules,” said Keith Hutchison, Vice President of R&D at Capsugel. “We want to make pharmaceutical and biotech companies aware that we now provide intelligently designed capsules and unique capsule dosing technology, either as standalone products or as part of an integrated drug delivery solution. Companies considering applications as diverse as drug delivery via DPI or developing the formulation of a poorly water soluble compound should come and explore our capabilities because we may help their development, reduce the time-line into clinic, and ultimately to market.”

Capsugel EMEA