Tuesday 14 September 2010

Rapid removal of phospholipids gives scientists new tool to advance drug discovery and development efforts

Waters Corporation's Ostro Sample Preparation Plate represents a novel approach for the removal of phospholipids from biological samples. When compared to other phospholipid removal devices and traditional liquid-liquid extraction (LLE) methods, Ostro removes up to 30 times more phospholipids.

Phospholipids have been cited as a major cause of matrix effects in the LC/MS analysis of biological samples. Ostro, with its proprietary, patent-pending design, was specifically created to overcome this hurdle by offering a “best-in-class” solution that removes multiple families of phospholipids.

The Ostro 96-well plate format utilizes in-well protein precipitation with a single, rapid, pass-through method that provides a quick, reliable, and reproducible solution.

Dr Diane Diehl, Director, Sample Preparation, Waters Division, said: “Ostro will be a valuable tool for researchers who are struggling with phospholipid interferences, and provide a complimentary solution to Oasis® SPE products - Waters premier solid-phase extraction solution.”

Waters Corporation