Thursday 30 September 2010

Speed chemotaxis research

TTP LabTech has today announced a high throughput solution for chemotaxis research using the Acumen eX3 microplate cytometer and the iuvo Chemotaxis Assay Plate from BellBrook Labs. Using this system, approximately four-fold time savings were achieved compared to a similar method using automated microscopy and off-line data processing.

The Acumen eX3 is a laser scanning microplate cytometer for the analysis of fluorescence in cell-based assays.
In addition to offering enhanced multiplexing functionality, Acumen eX3 has a wide field of view that enables whole well and microchannel scanning. The iuvo Chemotaxis Assay Plate is a high-content, automation friendly microconduit array plate that facilitates horizontal chemotaxis in the presence of a defined gradient. The combination of Acumen eX3 with the iuvo microchannels results in a rapid and robust approach to neutrophil chemotaxis studies.

This development offers scientists another assay that can be quickly and easily used as part of a primary screening oncology campaign.

Dr Paul Wylie, Acumen Product Manager, TTP LabTech comments: “This has proved a successful combination of products for customers involved with chemotaxis as the Acumen eX3 and iuvo plates offer an efficient alternative to the more traditional microscopy set-up requiring further off-line analysis.” he continued, “Setting up a good gradient often poses a challenge, but the iuvo plates eradicate this issue. The Acumen offers a fast and accurate analysis of the chemotaxis assay and whole well scanning enables multiple cell movements to be captured and analysed within any one well.”

TTP LabTech Ltd