Thursday 7 October 2010

Interactive resource for routine 3D cell culture

Reinnervate, a life sciences company driving the adoption of routine 3D cell culture, today announced the launch of its new, fully interactive website. The site is designed to provide an essential source of scientific and technical information on 3D cell culture based on reinnervate’s core Alvetex technology for academic and industrial researchers, teachers, students and the media.

Alvetex is a scaffold that enables routine 3D cell culture in the lab. By enabling cells to grow in a 3D environment, Alvetex better mimics the conditions experienced by cells when growing in normal tissue. Use of Alvetex therefore provides a more relevant and representative model for investigating how cells and tissues may behave in the body in response to external factors (such as drug candidates) than is currently possible with existing 2D or other emerging 3D cell culture technologies.
Professor Stefan Przyborski, reinnervate’s founder and Chief Scientific Officer, commented: “With the launch of our new website, reinnervate offers users of Alvetex an indispensable technical resource that provides not just news about our products but detailed technical information about how to use them. The site includes a library of cell culture protocols, technical Q&A and a selection of published papers exemplifying the use of Alvetex® in a variety of alternative cell types and applications.”

He added: “Through the site’s interactive forum, members of the scientific community can post their own research data, presentations and technical questions on to the website for discussion and use by fellow investigators.”

Ashley Cooper, CEO of reinnervate, said: “The new interactive website is a further step by reinnervate towards its goal of becoming a leading authority on 3D cell culture based on our revolutionary Alvetex technology. We plan to build an extensive library of validated cell culture protocols and other technical information and will be encouraging the scientific community to post their own protocols on this web site, via the reinnervate forum, for the benefit of fellow researchers.”

Alvetex provides a microscale environment that supports genuine homogeneous 3D cell growth. Cells grown using Alvetex form complex 3D tissue cultures, which more closely mimic normal in-vivo cell growth and the formation of tissues in the body. The use of Alvetex-derived 3D cell cultures can provide researchers with greater insight into how cells behave in the body in response to external factors (such as drug candidates) than is currently possible with existing 2D or other emerging 3D cell culture technologies. Importantly, Alvetex has been designed as an easy-to-use, off the shelf consumble product, that requires no specialist ancillary equipment and works within conventional cell culture plastic ware.

Reinnervate has generated significant data, which have been published extensively in peer-reviewed publications, exemplifying the use of Alvetex in a variety of cell types and applications. Alvetex is being developed for commercialisation in a range of formats and is due to be formally launched in November 2010.

Reinnervate is also using its cell biology expertise to generate a library of synthetic small molecules that mediate stem cell differentiation in vitro. The first of these small molecules, ec23, is commercially available and offers the potential for robust and reproducible differentiation of neural cell types.

Reinnervate
www.reinnervate.com