Evitria SA, a protein design and expression company, has achieved a major breakthrough in transient gene expression. Using Life Technologies’ Invitrogen FreeStyle CHO-S Cells, evitria scientists succeeded in obtaining titers exceeding 1 gram per litre in transient. evitria’s rapid protein expression platform now allows companies to perform their in vitro and in vivo studies with protein transiently produced in the same host system as used later for production of stable cell lines.
Comments Dr Sebastien Chenuet, Founder and Principal Investigator at evitria: “Today, CHO cells are the preferred host system for stable cell lines. Yet, many companies perform their initial in vitro and in vivo studies with protein transiently produced in HEK293 cells. We see the reason for that in the challenge to produce sufficient amounts of protein transiently in CHO cells. Going forward, evitria’s rapid protein expression platform will enable companies to perform their preclinical and clinical studies with the same host system. This is especially crucial in light of the extensive literature that stresses the importance of glycosylation on protein functionality.”
evitria SA
