Small pore size suits reduction of Mycoplasma in samples

The new Sterilin specialist filtration range enables life scientists to find a syringe filter or filtration unit with a pore size and membrane type to suit their most needs

The new Sterilin range of specialist filtration products is so extensive that life scientists are sure to be able to find a syringe filter or filtration unit with a pore size and membrane type to suit almost every application.

Choosing the correct pore size to suit a specific application is an important consideration when choosing a filter. Sterilin Syringe filters are available with pore sizes of 0.22μm and 0.45μm, and Sterilin Filtration Units in pore sizes of 0.10μm, 0.22μm and 0.45μm. The smallest pore size is ideal for the reduction of Mycoplasma in samples. 0.22μm filters are appropriate for applications such as sterilisation of media and aqueous solutions, filtration of buffers, protein binding and gas filtration/air monitoring. The largest pore size is suitable for the clarification of aqueous solutions and solvents, pre-filtration, filtration of protein-free media, solvents and aggressive chemicals, and for the sterilisation/ultra-cleaning of aqueous solutions.

Sterilin Syringe Filters with a PES (polyethersulfone) membrane demonstrate faster flow rates compared to other membrane types, with low protein binding and low levels of extractables. This membrane is suitable for the pre-filtration and filtration of buffers and culture media. Additionally, Sterilin Syringe Filters are also available with a CA (cellulose acetate) membrane.

Sterilin Filtration Units are available with a choice of PES, MCE, PVDF or NY filters.

MCE (mixed cellulose ester) is effective for the binding of trace proteins and is an excellent substitute for CA or CN (cellulose nitrate) membranes. PVDF (polyvinylidene fluoride) exhibits extremely low protein binding, which is important when maximising protein recovery. This membrane is also ideal for the filtration of non-aggressive aqueous solutions and mild organic solvents. Finally, NY (nylon) membranes have excellent chemical resistance. They are hydrophobic and can be used with a broad pH range.

Sterilin filtration products are gamma irradiated and ceritified non-pyrogenic to <0.5EU/mL to ensure that the quality of valuable samples is protected. In addition, the Syringe Filters and Filtration Units are individually wrapped to minimise the risk of contamination. For further protection against contamination, the caps supplied with the complete Filter Units are individually wrapped in order that sterility is maintained until the sample has been filtered.

The Sterilin Filtration Unit is manufactured using virgin non-toxic polystyrene for excellent clarity, with convenient moulded graduations. It has easy grip sides to improve handling and an ergonomic cap design for comfort and ease of use. It is available in a choice of volumes (150mL, 250mL, 500mL and 1L) and the 45mm screw thread is compatible with most manifolds. The Unit has been pressure tested to ensure leak-free performance.

Sterilin





The new Sterilin specialist filtration range enables life scientists to find a syringe filter or filtration unit with a pore size and membrane type to suit their most needs.